Von Willebrand factor and ADAMTS13 in hemostasis and thrombosis

09.00

Von Willebrand factor self-association role in hemostasis and thrombosis
José Lopez (USA)

09.30

Interactions of VWF/ADAMTS13
Jim Crawley (UK)

10.00

Modulation of ADAMTS13 conformation (open/close) in infection and other triggering conditions for TTP
Karen Vanhoorelbeke (Belgium)

10.30

Impact of cohort studies on therapeutic approaches for von Willebrand disease (VWD)
Jeroen Eikenboom (Netherlands)

11.00

Break

11.30

Update on 3WINTERS
Augusto B. Federici (Italy)

12.00

Acquired VWD
Giancarlo Castaman (Italy)

12.30

Role of von Willebrand factor in the vessel wall: interplay with vascular smooth muscle cells
Cécile Denis (France)

13.00

Lunch

14.00

Satellite Symposium/Lectures

Other clinical challenges of hemophilia

15.00

Thrombosis in hemophilia: results from EUHASS Registry, including thrombotic microangiopathies
Mike Makris (UK)

15.30

Ageing with hemophilia
Pier Mannuccio Mannucci (Italy)

16.00

Break

Immunotolerance induction in hemophilia (part II)

16.30

Gene-therapy-mediated tolerance induction
Valter R Arruda (USA)

17.00

A working group on new concepts for ITI
Kate Pratt (USA)

17.30

Predictive markers of persistent inhibitors: which patients could benefit from ITI?
Flora Peyvandi (Italy)